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Department of Chemistry and Biochemistry
Titelbild

Chemical & Biochemical Analyses

 

Deutsch / English

 

Methods

  • low- and high-resolution MS
  • ESI and MALDI ionization
  • accurate mass by ESI-MS
  • tandem MS
  • LC/MS and LC/MS/MS
  • Edman degradation
  • amino acid analysis: pre-column derivatization with PITC

Applications

  • structure elucidation and verification
  • purity and quality control
  • elemental composition
  • analysis of mixtures
  • identification of modifications
  • amino acid composition: bound and free amino acids
  • peptide and protein identification
  • sequencing of biopolymers (also de novo): peptides, proteins, and oligonucleotides

Equipment

  • LTQ Orbitrap XL with nano ESI (Thermo)
  • Autoflex Smartbeam III MALDI-TOF-MS (Bruker)
  • QTrap 5500 LC/MS/MS (Sciex)
  • QStar Pulsar ESI-qTOF-MS (Sciex)
  • Procise 492 cLC (Applied Biosystems)
  • Summit HPLC (Dionex)

Contacts

 

PD Dr. Stefan Schürch

Tel: +41 31 631 43 89
Fax: +41 31 631 34 21
E-mail: stefan.schuerch@dcb.unibe.ch
Homepage: http://schuerch.dcb.unibe.ch

 

 
Universität Bern | Department of Chemistry and Biochemistry | Freiestrasse 3 | CH-3012 Bern |
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