Chemical & Biochemical Analyses
Methods
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low- and high-resolution MS
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ESI and MALDI ionization
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accurate mass by ESI-MS
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tandem MS
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LC/MS and LC/MS/MS
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Edman degradation
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amino acid analysis: pre-column derivatization with PITC
Applications
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structure elucidation and verification
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purity and quality control
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elemental composition
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analysis of mixtures
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identification of modifications
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amino acid composition: bound and free amino acids
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peptide and protein identification
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sequencing of biopolymers (also de novo): peptides, proteins, and oligonucleotides
Equipment
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LTQ Orbitrap XL with nano ESI (Thermo)
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Autoflex Smartbeam III MALDI-TOF-MS (Bruker)
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QTrap 5500 LC/MS/MS (Sciex)
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QStar Pulsar ESI-qTOF-MS (Sciex)
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Procise 492 cLC (Applied Biosystems)
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Summit HPLC (Dionex)
Contacts
PD Dr. Stefan Schürch
Tel: +41 31 631 43 89
Fax: +41 31 631 34 21
E-mail: stefan.schuerch@dcb.unibe.ch
Homepage: http://schuerch.dcb.unibe.ch
Universität Bern |
Department of Chemistry and Biochemistry |
Freiestrasse 3 |
CH-3012 Bern |